\documentclass [12pt]{article}
\usepackage {multicol}


\begin{document}
Resuelve:
\begin{enumerate}

\begin{multicols}{4}
\item $\frac{2}{3}$de 72
\item $\frac{5}{9}$de 81
\item $\frac{2}{10}$de 1000
\item $\frac{4}{7}$de 49
\item $\frac{2}{9}$de 81
\item $\frac{7}{3}$de 81
\item $\frac{24}{3}$de 1234
\item $\frac{7}{3}$de 12
\item $\frac{2}{5}$de 65
\item $\frac{3}{5}$de 25
\item $\frac{1}{4}$de 100
\item $\frac{1}{3}$de 75
\item $\frac{2}{7}$de 35
\item $\frac{4}{5}$de 150
\item $\frac{6}{10}$de 1250
\item $\frac{3}{5}$de 20
\item $\frac{6}{12}$  de 84
\item $\frac{5}{10}$de 92
\item $\frac{15}{100}$de 3000
\item $\frac{4}{5}$de 45
\item $\frac{9}{20}$de 140
\item $\frac{4}{5}$de 30
\item $\frac{3}{6}$de 12
\item $\frac{3}{6}$de 36
\item $\frac{2}{3}$de 18
\item $\frac{2}{10}$de 65
\item $\frac{6}{14}$de 14
\item $\frac{5}{8}$de 136
\item $\frac{4}{6}$de 120
\item $\frac{2}{5}$de 20
\item $\frac{6}{25}$de 250
\item $\frac{3}{4}$de 124
\item $\frac{7}{8}$de 2200
\item $\frac{2}{5}$de 110
\item $\frac{2}{4}$de 52
\item $\frac{3}{5}$de 40
\item $\frac{6}{9}$de 81
\item $\frac{2}{5}$de 15
\item $\frac{6}{8}$de 1800
\item $\frac{3}{7}$de 28
\item $\frac{2}{6}$de 36
\item $\frac{6}{10}$de 110
\item $\frac{4}{5}$de 40
\item $\frac{5}{6}$de 12
\item $\frac{3}{7}$de 56
\item $\frac{1}{4}$de 124
\item $\frac{8}{10}$de 44
\item $\frac{2}{7}$de 14

\end{multicols}
\end{enumerate}


\end{document}